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Pilot projects provide opportunities for early career faculty and fellows to engage in exploratory science relevant to the central Conte Center hypothesis.   Projects are expected to influence the future trajectory of Center science and/or lead to attractive spin-offs

 

2014

1)  Relationship between Sleep Disturbance and Kynurenic Acid
Ana Pocivavsek

2)  Stress Biomarkers in Schizophrenia: Kynurenic Acid Response to Somatic versus Psychological Stressors
Joshua Chiappelli

2015

1)   Impact of Prenatal Kynurenine Exposure on Mismatch Negativity (MMN) Production
Molly Erickson

2)  Attentional Effects of Embryonic Treatment with Kynurenine
Britta Hahn

3)  Effect of Probiotic Treatment on Kynurenine Pathway Metabolism
Francesca Notarangelo

2016

1)  Effect of Prenatal THC Treatment on KYNA Levels in utero
Sarah Beggiato

2)  Effects of Acute Tryptophan Depletion on Reinforcement Learning in Schizophrenia
James Waltz

3)  Relationship of Peripheral Cytokines to Neurobiology in Schizophrenia
Joshua Chiappelli

2017

1)  “Double-hit” Effects in Rats Treated Prenatally with THC  
Sarah Beggiato

2)  Efficacy of NAC for Cognitive Enhancement in Early Phase Schizophrenia
Laura Rowland

3)  SNPs of Selected Kynurenine Pathway Genes: Relationship to Kynurenic acid Levels and Kynurenine 3-monooxygenase Activity in the Human Brain
Korrapati Sathayasaikumar

2018

1)  Prenatal Kynurenine Treatment in Mice: Effects on Neurogenesis
Gloria Hoffman

2)  Acute Effects of Kynurenine in Miniature Pigs: Exploring a New Translational Model
Peter Kochunov 

3) Inter-hemispheric Transmission in Mice with Genetic Elimination of Distinct Kynurenine Pathway Enzymes
Paul Shepard